Cerebrospinal fluid lactate level as a diagnostic biomarker for bacterial meningitis in children, International Journal of Emergency Medicine
Por um escritor misterioso
Descrição
Cerebrospinal fluid (CSF) lactate is a potential biomarker for bacterial meningitis in children. To this end, we performed a single-center retrospective cohort study of children from Sao Paulo, Brazil, with CSF pleocytosis to evaluate the ability of CSF lactate to distinguish between children with bacterial and aseptic meningitis. We determined the optimum cutoff point for CSF lactate using receiver-operator curve (ROC) analysis. We identified 451 children of whom 40 (9%) had bacterial meningitis. Children with bacterial meningitis had a higher median CSF lactate level [9.6 mmol/l, interquartile range (IQR) 3.2-38.5 mmol/l bacterial meningitis vs. 2.0 mmol/l, IQR 1.2-2.8 mmol/l aseptic meningitis]. A CSF lactate cutoff point of 3.0 mmol/l had a sensitivity of 95% [95% confidence interval (CI) 83-99%), specificity of 94% (95% CI 90-96%) and negative predictive value of 99.3% (95% CI 97.7-99.9%) for bacterial meningitis. In combination with a validated meningitis clinical prediction rule, the CSF lactate level can be used to distinguish between bacterial and aseptic meningitis in children with CSF pleocytosis.
Frontiers Comparing Single vs. Combined Cerebrospinal Fluid Parameters for Diagnosing Full-Term Neonatal Bacterial Meningitis
Neutrophil-to-lymphocyte ratio is associated with increased cerebral blood flow velocity in acute bacterial meningitis
Paired analysis of the groups showing the glucose average in CSF (mg/dL).
Aseptic and Bacterial Meningitis: Evaluation, Treatment, and Prevention
Cerebrospinal fluid lactate level as a diagnostic biomarker for bacterial meningitis in children, International Journal of Emergency Medicine
Diagnostics, Free Full-Text
PDF) CSF Lactate -An Independent and Reliable Biomarker among the CSF Parameters to Differentiate Bacterial Meningitis from Aseptic Meningitis
Biomedicines, Free Full-Text
Cerebrospinal fluid lactate: a differential biomarker for bacterial and viral meningitis in children - ScienceDirect
SciELO - Brasil - Comparison of cerebrospinal fluid lactate with physical, cytological, and other biochemical characteristics as prognostic factors in acute bacterial meningitis Comparison of cerebrospinal fluid lactate with physical, cytological, and
Application of metabolomics in diagnostics and differentiation of meningitis: A narrative review with a critical approach to the literature - ScienceDirect
PDF) Cerebrospinal fluid lactate level as a diagnostic biomarker for bacterial meningitis in children
PDF) Role of cerebro spinal fluid lactate as a diagnostic marker for differentiation from bacterial and aseptic meningitis
de
por adulto (o preço varia de acordo com o tamanho do grupo)
