Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease - Ruđer Bošković Institute
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The goal of this project is to elucidate the molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease (NPC). We will investigate the role of protease BACE1, the key Alzheimer's disease (AD) enzyme, in the pathogenesis of NPC disease. We hope that our findings will elucidate BACE1 as a novel target for treating/ameliorating NPC disease.
Molecular profile and peripheral markers of neurodegeneration in
Marko Košiček - Science communication coordinator - Ruđer Bošković
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C
Our research - Ruđer Bošković Institute
Self-propagation of pathogenic protein aggregates in
Niemann–Pick type C disease: cellular pathology and
PDF) Overlapping Neuroimmune Mechanisms and Therapeutic Targets in
PDF) N-glycome of the lysosomal glycocalyx is altered in Niemann
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por adulto (o preço varia de acordo com o tamanho do grupo)